Thermo Fisher Scientific PITRM1 Polyclonal Antibody
PITRM1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P)에서 검증됨. Human, Mouse, Rat에 반응하며 항원 친화 크로마토그래피로 정제됨. Alzheimer’s disease 관련 연구에 유용. 연구용으로만 사용 가능.
- 카탈로그번호
- PA552340
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PITRM1. Recombinant protein control fragment (Product #RP-89249) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645586 |
Product Specific Information
Immunogen sequence:
LEHTVLCGSQ KYPCRDPFFK MLNRSLSTFM NAFTASDYTL YPFSTQNPKD FQNLLSVYLD ATFFPCLREL DFWQEGWRLE HENPSDPQTP LVFKGVVFNE MKGAFTDNER IFSQHLQNRL LPDHTYSVVS
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 97%
Target Information
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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