Thermo Fisher Scientific ANP32C Monoclonal Antibody (OTI10A10)
ANP32C 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot 및 IHC(P) 분석에 적합합니다. Human 시료에 반응하며, 고순도의 Affinity Chromatography 정제 항체입니다. 안정적인 액상 형태로 -20°C 보관 시 장기 안정성을 유지합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10A10 |
| Immunogen | Full length human recombinant protein of ANP32C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2722868 |
Target Information
ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 or tumorigenic protein pp32r1, is a 234 amino acid protein that contains four leucine-rich repeats and belongs to the ANP32 family.
ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor inhibiting cancers such as prostate and breast cancer.
Although similar to ANP32A, ANP32C is tumorigenic and is expressed in activated stem cells (mobilized CD34+ cells, cord blood CD34+ cells) but not in resting bone marrow CD34+ cells.
It is also expressed in various neoplastic cell lines, primarily in prostatic adenocarcinoma cell lines, but not in normal prostatic tissue, and may modulate the oncogenic potential of human prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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