Thermo Fisher Scientific KRT81 Polyclonal Antibody
KRT81 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. Human 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KRT81 (Accession Q14533), corresponding to amino acid residues P470–C505 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850350 |
Product Specific Information
Antibody detects endogenous levels of total KRT81.
Target Information
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein that heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structural similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related, while the other subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin, as well as KRTHB3 and KRTHB6, is primarily found in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with the rare dominant hair disease, monilethrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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