Thermo Fisher Scientific MCF2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MCF2 protein. Validated for Western blot at 1:500–1:2,000 dilution. Detects endogenous MCF2 levels. Supplied as liquid, unconjugated form with 1 mg/mL concentration. Suitable for research use only.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MCF2 (Accession P10911), corresponding to amino acid residues P721–G771 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850351 |
Product Specific Information
Antibody detects endogenous levels of total MCF2.
Target Information
Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes conversion of Rho family GTPases from GDP-bound to GTP-bound forms.
- Isoform 1: No activity toward RHOA, RAC1, or CDC42
- Isoform 2: Decreased GEF activity toward CDC42
- Isoform 3: Weak but significant activity toward RAC1 and CDC42
- Isoform 4: Significant activity toward RHOA and CDC42
- Truncated DBL oncogene: Active toward RHOA, RAC1, and CDC42
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-100853_MCF2_P10911-1_Rabbit.svg, PA5-100853_MCF2_P10911-1_Rabbit_PDP.jpeg)
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