Thermo Fisher Scientific DDHD1 Polyclonal Antibody
Rabbit에서 유래한 DDHD1 단백질 인식 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 DDHD1의 50-100번 잔기 영역을 면역원으로 사용하였으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 50 to 100 of human Phospholipase DDHD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene belongs to the intracellular phospholipase A1 gene family. The encoded protein preferentially hydrolyzes phosphatidic acid and is mainly cytosolic with partial mitochondrial localization. It plays a role in regulating mitochondrial dynamics.
Overexpression of this gene leads to mitochondrial fragmentation, while depletion causes elongation of mitochondrial tubules. Deletion in male mice results in fertility defects due to disrupted mitochondrial organization during spermiogenesis. In humans, mutations are associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease or familial spastic paraparesis (FSP), characterized by progressive leg weakness and spasticity. Alternative splicing produces multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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