Thermo Fisher Scientific Phospho-Chk1 (Ser317) Recombinant Rabbit Monoclonal Antibody (Chk1S317-G1), FITC
FITC 형광 표지된 Phospho-Chk1 (Ser317) 재조합 토끼 단클론 항체로, 인간 및 생쥐 시료에서 Flow Cytometry에 적합합니다. HEK293 세포에서 발현되었으며, Protein A/G로 정제된 액상 형태입니다. DNA 손상 반응 및 세포 주기 조절 연구에 활용됩니다.
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Thermo Fisher Scientific Phospho-Chk1 (Ser317) Recombinant Rabbit Monoclonal Antibody (Chk1S317-G1), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Chk1S317-G1 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897002 |
Additional Formats
Target Information
CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised. CHK1 is a key mediator in the DNA damage-induced checkpoint network and functions to ensure genomic integrity under genotoxic stress. Inhibition of CHK1 can lead to mitotic catastrophe in p53-deficient cancer cells, making Chk1 an attractive target for cancer therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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