Thermo Fisher Scientific ZIC2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.5–2 µg/mL

Product Specifications

Product Specific Information

• This antibody is expected not to cross-react with other ZIC proteins.
• Tested in Peptide ELISA: antibody detection limit dilution 1:1,000.

Target Information

ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor that may regulate tissue-specific expression of dopamine receptor D1.
In mouse, knockout of Zic1 leads to aplasia of the cerebellum and skeletal abnormalities.
Mutations in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively.
Holoprosencephaly is the most common structural anomaly of the human brain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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