Thermo Fisher Scientific cGKI Polyclonal Antibody, FITC
FITC로 결합된 cGKI 폴리클로날 항체로, Western blot, ELISA, IP 등에 사용 가능. 사람, 마우스, 랫트 반응성. Rabbit IgG 유래로 특이적 결합력 우수. 액상 형태로 -20°C 어두운 곳에 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 609–659 of human protein kinase G alpha subunit (PRKG1). |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PRKG1 (cGMP-dependent serine/threonine kinase) plays a key role in vascular smooth muscle relaxation and inhibition of platelet aggregation. It is central to cardiovascular and neuronal regulation, smooth muscle tone relaxation, and modulation of cell growth.
Highly expressed in smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala.
Isoforms Iα and Iβ share identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences, leading to distinct dimerization and kinase activity profiles.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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