Thermo Fisher Scientific PRUNE2 Polyclonal Antibody
Human PRUNE2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며, 비결합형 액상 형태. 신경계 및 다양한 암 세포주 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PRUNE2. Recombinant protein control fragment (Product #RP-93020) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646040 |
Product Specific Information
Immunogen sequence:
MESEKISEKQ EEILSILEEK FPNLPPREDI INVLQETQFS AQGLSIEQTM LKDLKELSDG EIKVAISTVS MNLEVRVGML
Antigen sequence identity:
- Mouse: 75%
- Rat: 75%
Target Information
PRUNE2 gene (also known as BMCC1) encodes the protein prune homolog 2. PRUNE2 overlaps with PCA3, one of the most prostate cancer–specific markers. It may play an important role in regulating differentiation, survival, and aggressiveness of tumor cells.
PRUNE2 is highly expressed in the nervous system (brain, cerebellum, and spinal cord) and in certain cancer cell lines such as neuroblastoma, rhabdomyosarcoma, melanoma, and osteosarcoma. Expression is lower in liver, breast, thyroid, and colon cancer cell lines.
The calculated molecular weight of this protein is 340 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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