Thermo Fisher Scientific PCSK5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PCSK5. Recombinant protein control fragment (Product #RP-89239). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PCSK5,uniProtId:Q92824-1,ncbiNodeId:9606,antigenRange:504-626,antigenLength:1860,antigenImageFileName:PA5-56631_PCSK5_Q92824-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56631_PCSK5_Q92824-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645303

Product Specific Information

Immunogen sequence: YLEHVVVRIT ITHPRRGDLA IYLTSPSGTR SQLLANRLFD HSMEGFKNWE FMTIHCWGER AAGDWVLEVY DTPSQLRNFK TPGKLKEWSL VLYGTSVQPY SPTNEFPKVE RFRYSRVEDP TDD

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.