Thermo Fisher Scientific Transthyretin Monoclonal Antibody (3-E11)
인간 Transthyretin 단백질을 인식하는 Mouse IgG2b 단클론 항체입니다. Western blot에 최적화되어 있으며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3-E11 |
| Immunogen | Synthetic peptide within human Prealbumin PA aa 100–147 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 40% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931097 |
Target Information
Transthyretin (TTR), also known as prealbumin, is a plasma protein that functions as a transporter for thyroxine and retinol-binding protein. It is primarily synthesized in the liver and secreted into plasma. TTR constitutes approximately 25% of cerebrospinal fluid (CSF) protein, suggesting selective transport across the blood-CSF barrier or synthesis within the central nervous system. It has been identified in neuritic plaques, neurofibrillary tangles, and microangiopathic lesions associated with senile cerebral amyloid. Over 40 mutations in the TTR gene have been linked to amyloid deposition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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