Thermo Fisher Scientific COL7A1 Monoclonal Antibody (LH7.2)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 4 publications 4 publications

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Immunomicroscopy (IM)

Assay-dependent

-

Product Specifications

Species Reactivity

Bovine, Guinea pig, Goat, Human, Non-human primate, Sheep, Pig

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

LH7.2

Immunogen

Insoluble fractions of human neonatal foreskin epidermal cells if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:COL7A1,uniProtId:Q02388-1,ncbiNodeId:9606,antigenRange:1-2944,antigenLength:2944,antigenImageFileName:MA5-13432_COL7A1_Q02388-1_House_mouse.svg,antigenImageFileNamePDP:MA5-13432_COL7A1_Q02388-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10980671

Product Specific Information

MA5-13432 targets Collagen VII in IF, IHC (F), and IM applications and shows reactivity with Bovine, Guinea Pig, Goat, Human, Non-human primate, Ovine, and Porcine samples.

The MA5-13432 immunogen is insoluble fractions of human neonatal foreskin epidermal cells.

Target Information

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.