Thermo Fisher Scientific CXCL13 Polyclonal Antibody
CXCL13 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ELISA에 적합하며, 항원 친화 크로마토그래피로 정제됨. Lyophilized 형태로 제공되며, 재구성 후 500 µg/mL 농도 유지. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL | View 1 publication |
| ELISA | 0.1–0.5 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived mouse BCA1 recombinant protein (Position: I22–A109) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2746222 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
CXCL13, also known as BCA-1 and Angie, is a small chemokine strongly expressed in secondary lymphoid organs. It promotes migration of B lymphocytes (B-1 and B-2) to follicles of spleen, lymph nodes, and Peyer’s patches. Produced by macrophages, especially large peritoneal macrophages, Kupffer cells, and lung macrophages.
The cellular ligand for CXCL13 is CXCR5 (BLR-1), expressed on B cells, Tfh cells, and some memory T cells. CXCL13 is implicated in chronic lymphocytic leukemia (CCL) and serves as a plasma biomarker for germinal center activity and broadly neutralizing antibody generation against HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(관련 항원 구조 이미지: PA5-79106_CXCL13_O55038-1_Rabbit.svg, PA5-79106_CXCL13_O55038-1_Rabbit_PDP.jpeg)
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