Thermo Fisher Scientific CXCL13 Polyclonal Antibody
CXCL13 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 인간 시료 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며 재구성 후 500 µg/mL 농도로 사용 가능합니다.
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Applications
- Western Blot (WB): 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human BCA1 recombinant protein (Position: V23–P109) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2746221 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
CXCL13 (also known as BCA-1 and Angie) is a small chemokine strongly expressed in secondary lymphoid organs. It promotes migration of B lymphocytes (B-1 and B-2) to follicles of the spleen, lymph nodes, and Peyer’s patches. CXCL13 is produced by macrophages, including large peritoneal macrophages, Kuppfer cells, and lung macrophages (CD11c+ and CD11c−).
Its cellular ligand, CXCR5 (also known as BLR-1), is expressed on B cells, Tfh cells, and some memory T cell populations. CXCL13 plays a role in chronic lymphocytic leukemia (CCL) development and serves as a plasma biomarker for germinal center activity and broadly neutralizing antibody generation against HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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