Thermo Fisher Scientific PPIG Polyclonal Antibody
Human PPIG에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품이며 PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Thermo Fisher Scientific PPIG Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPIG. Recombinant protein control fragment (Product #RP-103943) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791498 |
Product Specific Information
Immunogen sequence:
QRMRVSSGER WIKGDKSELN EIKENQRSPV RVKERKITDH RNVSESPNRK NEKEKKVKDH KSNSKERDIR RNSEKEDKYK NKVKKRAKSK S
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression. These chromo proteins are conserved in eukaryotes and mutations can lead to mitotic chromosome segregation defects, indicating a critical function of SMC family proteins in mitotic chromosome dynamics.
SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells, specifically responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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