Thermo Fisher Scientific TMEM16B Polyclonal Antibody
인간 TMEM16B 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P)에서 1:1,000–1:2,500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.1 mg/mL 농도의 액상 형태. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ANO2. Recombinant protein control fragment (Product #RP-108423) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791500 |
Product Specific Information
Immunogen sequence:
EPVSLEARLS RMHFHDSQRK VDYVLAYHYR KRGVHLAQGF PGHSLAIVSN GETGKEPHAG GPGDIELGPL DALEEERKEQ REEFEHNLM
Target Information
Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCCs include the transmembrane proteins TMEM16A and TMEM16B.
TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina.
Like TMEM16A, TMEM16B is thought to form at least part of CaCCs but has different biophysical characteristics such as voltage dependence and unitary conductance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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