Thermo Fisher Scientific TMEM16B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ANO2. Recombinant protein control fragment (Product #RP-108423). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TMEM16B,uniProtId:Q9NQ90-1,ncbiNodeId:9606,antigenRange:79-167,antigenLength:1003,antigenImageFileName:PA5-84348_TMEM16B_Q9NQ90-1_Rabbit.svg,antigenImageFileNamePDP:PA5-84348_TMEM16B_Q9NQ90-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791500

Product Specific Information

Immunogen sequence: EPVSLEARLS RMHFHDSQRK VDYVLAYHYR KRGVHLAQGF PGHSLAIVSN GETGKEPHAG GPGDIELGPL DALEEERKEQ REEFEHNLM

Target Information

Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCCs include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCCs but has different biophysical characteristics such as voltage dependence and unitary conductance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.