Thermo Fisher Scientific RhoGAP Polyclonal Antibody
RhoGAP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P)에서 검증됨. Human과 Mouse에 반응하며, 고순도 항원 친화 크로마토그래피로 정제됨. 세포 신호전달 및 Rho/Rac GTPase 연구에 적합.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 158–406 of Human ARHGAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544902 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2, Mouse brain, ARHGAP1-transfected 293T
- Predicted reactivity: Mouse (95%), Rat (92%), Dog (96%), Rhesus Monkey (98%), Bovine (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The p190 RhoGAP protein is associated with p120 RasGAP in growth-factor stimulated and tyrosine kinase transformed cells. It functions as a GTPase-activating protein (GAP) for Rho and Rac family proteins, which regulate cytoskeletal actin and membrane ruffling. The antibody may couple Ras and Rho signal transduction through its association with RasGAP. The presence of two adjacent SH2 domains in p21 RAS GAP suggests direct interaction with tyrosine kinases.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-27426_RhoGAP_Q07960-1_Rabbit.svg, PA5-27426_RhoGAP_Q07960-1_Rabbit_PDP.jpeg)
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