Thermo Fisher Scientific Phospho-Btk (Tyr551) Recombinant Rabbit Monoclonal Antibody (BtkY551-G12), FITC
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA537368 | - | Thermo Fisher Scientific MA537368 Phospho-Btk (Tyr551) Recombinant Rabbit Monoclonal Antibody (BtkY551-G12), FITC 10 tests pk | 재고문의 | pk | 271,000원 | - | 298,100원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Flow Cytometry (Flow)
5 µL/1x10^6 cells
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
BtkY551-G12
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr551 of human phospho Btk. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
BTK,
uniProtId:
Q06187-1,
ncbiNodeId:
9606,
antigenRange:
551,
antigenLength:
659,
antigenImageFileName:
MA5-37368_BTK_Q06187-1_Rabbit.svg,
antigenImageFileNamePDP:
MA5-37368_BTK_Q06187-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
FITC FITC FITC
View additional formats
Excitation/Emission Max
498/517 nm View spectra
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS with 0.20% BSA
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897302
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9. The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens. BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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