Thermo Fisher Scientific Phospho-Btk (Tyr551) Recombinant Rabbit Monoclonal Antibody (BtkY551-G12), FITC
FITC로 표지된 재조합 토끼 단클론 항체로, 인산화된 Btk (Tyr551)을 특이적으로 인식합니다. 인간 시료에 반응하며, 유세포 분석(Flow Cytometry)에 적합합니다. Protein A/G로 정제되었으며, PBS 및 BSA 완충액에 보존됩니다. 연구용 전용 제품입니다.
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- MA537368
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- pk
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Applications and Tested Dilution
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BtkY551-G12 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr551 of human phospho Btk |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897302 |
Available Formats
- Unconjugated (Cat. No. MA5-37120)
- APC (Cat. No. MA5-37123)
- Biotin (Cat. No. MA5-37213)
- PE (Cat. No. MA5-37121)
- Custom conjugation available upon request
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily. Mutations in the BTK gene are associated with developmental blocks in human B-cell ontogeny and immunodeficiency disorders.
BTK interacts with toll-like receptor (TLR) family members such as TLR4, TLR6, TLR8, and TLR9, which play key roles in innate and adaptive immunity.
It also associates with signaling proteins including MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting involvement in lipopolysaccharide signal transduction.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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