Thermo Fisher Scientific TMPRSS6 Polyclonal Antibody, MaxPab
TMPRSS6 단백질을 인식하는 폴리클로날 항체로, Western blot에 적합합니다. 인간 시료 반응성이 있으며 액상 형태로 제공됩니다. PBS 버퍼에 보존제가 없으며, -20°C에서 보관해야 합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific TMPRSS6 Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TMPRSS6 (AAH39082.1, 1 a.a.–approximately 461 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MLLLFHSKRM PVAEAPQVAG GQGDGGDGEE AEPEGMFKAC EDSKRKARGY LRLVPLFVLL ALLVLASAGV LLWYFLGYKA EVMVSQVYSG SLRVLNRHFS QDLTRRESSA FRSETAKAQK MLKELITSTR LGTYYNSSSV YSFGEGPLTC FFWFILQIPE HRRLMLSPEV VQALLVEELL STVNSSAAVP YRAEYEVDPE GLVILEASVK DIAALNSTLG CYRYSYVGQG QVLRLKGPDH LASSCLWHLQ GPKDLMLKLR LEWTLAECRD RLAMYDVAGP LEKRLITSVY GCSRQEPVVE VLASGAIMAV VWKKGLHSYY DPFVLSVQPV VFQACEVNLT LDNRLDSQGV LSTPYFPSYY SPQTHCSWHL TVPSLDYGLA LWFDAYALRR QKYDLPCTQG QWTIQNRRYH FLSSLWLPFL PPPPSLPSST VTPSLEAQVP NLRGAARGAS RGWGWCQACC P
Target Information
TMPRSS6 is a serine protease that hydrolyzes proteins such as type I collagen, fibronectin, and fibrinogen. It can activate urokinase-type plasminogen activator with low efficiency and may play a role in matrix remodeling processes in the liver. TMPRSS6 is required for sensing iron deficiency, and its overexpression suppresses activation of the HAMP promoter. The encoded protein is a type II transmembrane serine proteinase found on the cell surface and may be involved in liver matrix remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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