Thermo Fisher Scientific IGSF3 Monoclonal Antibody (503621)
Human IGSF3 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 Flow cytometry에 적합. ELISA에서 높은 특이성과 무교차 반응성. Lyophilized 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 2 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 2.5 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 503621 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human IGSF3 (Gln20–Ala1125) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610102 |
Product Specific Information
- In direct ELISAs, no cross-reactivity with recombinant human (rh) IGSF4, 4B, 4C, 4D or 8 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein.
It is widely expressed, with predominant expression in kidney, placenta, and lung.
IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains, and a transmembrane segment.
It exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein believed to play a role in T-cell activation.
Despite structural similarities, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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