Thermo Fisher Scientific Thrombomodulin Monoclonal Antibody (501733)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

8-25 µg/mL

-

Flow Cytometry (Flow)

0.25 µg per million cells

-

ELISA (ELISA)

0.5-2 µg/mL (Detection), 2-8 µg/mL (Capture)

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

501733

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Thrombomodulin/BDCA-3 Ala19-Ser515 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Thrombomodulin (CD141),uniProtId:P07204-1,ncbiNodeId:9606,antigenRange:19-515,antigenLength:575,antigenImageFileName:MA5-24214_Thrombomodulin_CD141_P07204-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24214_Thrombomodulin_CD141_P07204-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2609660

Product Specific Information

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.