
Thermo Fisher Scientific TMPRSS11D Polyclonal Antibody
TMPRSS11D 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. WB 및 IHC 실험에 사용 가능하며, Protein A로 정제된 고순도 항체입니다. PBS buffer에 보관되며 -20°C에서 안정적으로 저장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 2.5 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human TMPRSS11D (aa 51-100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2610206 |
Product Specific Information
- Peptide sequence: RSSFQLLNVE YNSQLNSPAT QEYRTLSGRI ESLITKTFKE SNLRNQFIRA
- Sequence homology:
- Guinea Pig: 79%
- Horse: 79%
- Human: 100%
- Rabbit: 79%
Target Information
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that, with IL-17A, plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.
IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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