Thermo Fisher Scientific CDC25C Monoclonal Antibody (3B11)
CDC25C 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot 및 ELISA에 사용 가능. 인간 유래 단백질에 반응하며, 액상 형태로 제공. 세포 분열 조절 연구에 적합. -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B11 |
| Immunogen | CDC25C (AAH19089, 21 a.a. approximately 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
FRSNQRKMLN LLLERDTSFT VCPDVPRTPV GKFLGDSANL SILSGGTPKC CLDLSNLSSG EITATQLTTS ADLDETGHLD SSGLQEVHLA GMNHDQHLMK CSPAQLLCST
Target Information
M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene.
This gene is highly conserved during evolution and plays a key role in the regulation of cell division.
The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family.
It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis.
It is also thought to suppress p53-induced growth arrest.
Multiple alternatively spliced transcript variants of this gene have been described; however, the full-length nature of many of them is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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