
Thermo Fisher Scientific FOXRED2 Polyclonal Antibody
Thermo Fisher Scientific의 FOXRED2 폴리클로날 항체로 인간 FOXRED2 단백질 검출에 적합. WB와 ICC/IF에 사용 가능하며, 고순도 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 농도의 액상 형태로 제공되며, 2–8°C 보관 권장.
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Thermo Fisher Scientific FOXRED2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid synthetic peptide near the amino terminus of human FOXRED2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551697 |
Product Specific Information
- Suggested positive control: human lung tissue lysate
- PA5-34345 can be used with blocking peptide PEP-1388
Target Information
FOXRED2 (also known as ERFAD) is an endoplasmic reticulum luminal flavoprotein involved in ER-associated degradation (ERAD). It binds non-native proteins in the ER and targets them for ubiquitination and degradation. Knockdown of FOXRED2 delays degradation of ribophorin 332 and reduces polyubiquitinated protein levels. Related protein FOXRED1 defects cause mitochondrial complex I deficiency (MT-C1D), suggesting FOXRED2 may also play a role in MT-C1D.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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