Thermo Fisher Scientific PIWIL2 Polyclonal Antibody
Human PIWIL2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 인간 뇌 조직 lysate를 양성 대조군으로 사용할 수 있습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PIWIL2 Polyclonal Antibody
Applications
- Immunohistochemistry (IHC)
Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid synthetic peptide near the center of human PIWI-L2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551693 |
Product Specific Information
- Suggested positive control: Human brain tissue lysate
- PA5-34341 can be used with blocking peptide PEP-1384
Target Information
The piwi gene of Drosophila belongs to a novel class of evolutionarily conserved genes (the piwi or Argonaute family).
The Piwi family is required for germ and stem cell development in invertebrates, and two Piwi members, MIWI and MILI (Miwi-like, Piwil2, Piwi-like protein 2), are essential for spermatogenesis in mouse.
MIWI and MILI partner with Piwi-interacting RNAs (piRNAs), which are 26–31 nucleotides in length, distinct from microRNAs (miRNAs) or short interfering RNAs (siRNAs).
MILI may be programmed by distinct piRNA populations at different stages of germ cell development, suggesting its role in meiotic prophase progression.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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