Thermo Fisher Scientific Parkin Polyclonal Antibody
Parkin 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, ELISA, Immunoprecipitation에 사용 가능. 인간 Parkin 단백질의 390-440 아미노산 영역 합성 펩타이드로 면역화됨. 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 390–440 on human Parkin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The precise function of the Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation.
Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease.
Alternative splicing produces multiple transcript variants encoding distinct isoforms, with additional splice variants described but lacking transcript support.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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