Thermo Fisher Scientific SHP2 Monoclonal Antibody (246CT9.8.2)
SHP2 단클론 항체로 Western blot에 적합하며 인간 및 생쥐 반응성을 가짐. PTPN11 재조합 단백질을 면역원으로 사용. Protein G로 정제된 액상 항체로 4°C 단기, -20°C 장기 보관 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 246CT9.8.2 |
| Immunogen | PTPN11 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897452 |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate interaction with substrates. It is widely expressed in most tissues and plays a regulatory role in cell signaling events related to mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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