Thermo Fisher Scientific NeuroD1 Polyclonal Antibody
NeuroD1 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Thermo Fisher Scientific NeuroD1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human NeuroD1 (amino acids 21–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It binds to the insulin gene E-box, and efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein.
Defects in NEUROD1 are associated with maturity onset diabetes of the young type VI (MODY6), a form of non-insulin-dependent diabetes mellitus characterized by autosomal dominant inheritance, early adulthood onset, and impaired insulin secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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