Thermo Fisher Scientific CHMP2B Polyclonal Antibody
CHMP2B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도 Affinity chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관하며 연구용으로 사용됩니다.
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Thermo Fisher Scientific CHMP2B Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CHMP2B (Accession Q9UQN3), corresponding to amino acid residues D155–R205 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815760 |
Product Specific Information
Antibody detects endogenous levels of total CHMP2B.
Target Information
CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein.
Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta, and leukocytes, CHMP2B associates directly with CHMP2A and VPS4 for the disassembly of the ESCRT-III complex.
Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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