Thermo Fisher Scientific MALT1 Recombinant Rabbit Monoclonal Antibody (MT1, 3159R)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1–2 µg/mL

Product Specifications

Product Specific Information

• Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
• Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

MALT1/Paracaspase (MALT1)는 인간 paracaspase 계열의 구성원으로, B-cell lymphoma와 상호작용하는 단백질로 확인되었습니다 (Uren et al., 2000).
MALT1는 N-terminal death domain, 두 개의 Ig-like domain, 그리고 C-terminal caspase-like domain을 포함하는 caspase 유사 단백질입니다.
이 단백질은 Bcl10과 결합하여 NF-kappaB 활성화를 유도합니다.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.