Thermo Fisher Scientific PPBP Polyclonal Antibody, MaxPab
Thermo Fisher Scientific의 PPBP 폴리클로날 항체는 인간 단백질을 인식하는 Rabbit IgG로, Western blot에 적합합니다. 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4) 용액 형태로 제공됩니다. 염증 및 상처 치유 관련 연구용으로 적합합니다.
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Thermo Fisher Scientific PPBP Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB)
Tested Dilution
- 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | PPBP (NP_002695.1, 1–128 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSLRLDTTPS CNSARPLHAL QVLLLLSLLL TALASSTKGQ TKRNLAKGKE ESLDSDLYAE LRCMCIKTTS GIHPKNIQSL EVIGKGTHCN QVEVIATLKD GRKICLDPDA PRIKKIVQKK LAGDESAD
Target Information
Members of the α-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a similar motif (Cys-X-Cys) and are chemotactic for neutrophils.
The platelet basic protein (PBP), a member of this family, resides in platelet α-granules and is released upon activation. Proteolytic cleavage of its amino terminus generates several peptides including mature PBP, connective tissue-activating peptide III (CTAP III, also known as low affinity platelet factor IV), β-thromboglobulin (β-TG), and neutrophil-activating peptide 2 (NAP-2).
PBP and its truncated derivatives mediate inflammation and wound healing. Specifically, NAP-2 activates chemotaxis and degranulation in neutrophils during inflammation.
The gene encoding human PBP maps to chromosome 4q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: H00005473-D01P_PPBP_P02775-1_Rabbit.svg)
(이미지: H00005473-D01P_PPBP_P02775-1_Rabbit_PDP.jpeg)
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