Thermo Fisher Scientific EHMT1 Polyclonal Antibody
EHMT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에서 1:1000 희석으로 사용 가능. 인간에 반응하며, 마우스에서도 예측 반응. 고순도 정제 및 안정적 PBS buffer 포맷으로 연구용 적합.
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Thermo Fisher Scientific EHMT1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1145–1174 amino acids from the C-terminal region of human EHMT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980457 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
EHMT1, also known as EUHMTASE1, is a histone methyltransferase.
This protein methylates Lys-9 of histone H3 in vitro.
H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones.
EHMT1 is probably targeted to histone H3 by DNA-binding proteins such as E2F6, MGA, MAX, and/or DP1.
During G0 phase, it likely contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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