Thermo Fisher Scientific ACE Monoclonal Antibody (3H7E4)
ACE 단백질을 표적으로 하는 mouse monoclonal antibody로, Western blot, IHC, ICC, Flow cytometry, ELISA에 사용 가능. 인간 시료 반응성. Protein G 정제, 1 mg/mL 농도, PBS buffer에 sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H7E4 |
| Immunogen | Purified recombinant fragment of human CD143 (AA: extra 30–182) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4 °C (short term). For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090809 |
Target Information
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into the physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid–electrolyte balance. This enzyme plays a key role in the renin–angiotensin system. Studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with circulating enzyme levels and cardiovascular pathophysiologies. Two major alternatively spliced variants encode somatic and testicular isozymes that are equally active. Additional alternatively spliced variants have been identified, though their full-length structures remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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