Thermo Fisher Scientific RGS18 Polyclonal Antibody
Human RGS18 단백질에 특이적인 Rabbit Polyclonal Antibody로 Western Blot 및 IHC(Paraffin) 검증 완료. 항원 친화 크로마토그래피로 정제된 액상형 항체이며, PBS buffer(40% glycerol, 0.02% sodium azide) 포함. 연구용으로만 사용 가능.
- 카탈로그번호
- PA583792
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RGS18. Recombinant protein control fragment (Product #RP-94313). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790944 |
Product Specific Information
Immunogen sequence:
LFFSQINMCE SKEKTFFKLI HGSGKEETSK EAKIRAKEKR NRLSLLVQKP EFHEDTRSSR SGHLAKETRV SPEEAVKWGE S
Target Information
This gene encodes a member of the regulator of G-protein signaling family.
The protein contains a conserved, 120 amino acid motif called the RGS domain.
It attenuates G-protein signaling by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), accelerating conversion of GTP to GDP.
This hydrolysis allows G alpha subunits to bind G beta/gamma heterodimers, forming inactive G-protein heterotrimers and terminating the signal.
Alternate transcriptional splice variants have been observed but not thoroughly characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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