Thermo Fisher Scientific LRIG1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

5-15 µg/mL

-

Flow Cytometry (Flow)

2.5 µg per million cells

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Human embryonic kidney cell line HEK293-derived recombinant human LRIG1 Ala35-Ser779 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LRIG1,uniProtId:Q96JA1-1,ncbiNodeId:9606,antigenRange:35-779,antigenLength:1093,antigenImageFileName:PA5-47928_LRIG1_Q96JA1-1_Sheep.svg,antigenImageFileNamePDP:PA5-47928_LRIG1_Q96JA1-1_Sheep_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606053

Product Specific Information

In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse LRIG1 and and less 1% cross-reactivity with recombinant human LRIG3 is observed.

Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Target Information

LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a tumor suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.