Thermo Fisher Scientific LRIG1 Polyclonal Antibody
LRIG1 단백질을 인식하는 Sheep 유래 Polyclonal 항체로, Human 시료에 반응합니다. IHC(P) 및 Flow Cytometry에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, -20°C에서 보관합니다.
- 카탈로그번호
- PA547928
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL | - |
| Flow Cytometry (Flow) | 2.5 µg per million cells | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human embryonic kidney cell line HEK293-derived recombinant human LRIG1 (Ala35–Ser779) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606053 |
Product Specific Information
- In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse LRIG1 and less than 1% cross-reactivity with recombinant human LRIG3 is observed.
- Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
LRIG1 protein (UniProt ID: Q96JA1) is encoded by a gene located on chromosome band 3p14.3, a region often deleted in various human cancers. LRIG1 is considered a tumor suppressor gene in humans.
This integral cell-surface membrane protein is expressed in specific human tissues, with a 143-kDa form that may be cleaved into 111-kDa and 32-kDa fragments.
LRIG1 may inhibit the growth of glial cell tumors, and down-regulation of LRIG1 expression may contribute to tumor development and progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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