
Thermo Fisher Scientific Phospho-Ship2 (Tyr1135) Recombinant Rabbit Monoclonal Antibody (Ship2Y1135-1D2)
Phospho-Ship2 (Tyr1135) 인산화 부위를 특이적으로 인식하는 재조합 토끼 단클론 항체. 인간 및 생쥐 시료에 반응하며, 높은 특이성과 재현성을 제공. Flow Cytometry 등 다양한 응용에 적합. -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1–1,000 ng/mL |
Species Reactivity
Human, Mouse
Host / Isotype
Rabbit / IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
Ship2Y1135-1D2
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr1135 of human phospho Ship2.
Target Family: SHIP2
UniProt ID: O15357-1
Antigen Range: 1135
Antigen Length: 1258
Conjugate
Unconjugated
Additional Formats
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage Buffer
PBS, pH 7.4, with 0.1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage Conditions
-20°C
Shipping Conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2896977
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The encoded protein is an SH2-containing 5′-inositol phosphatase involved in the regulation of insulin function. It also regulates epidermal growth factor receptor turnover and actin remodeling. Additionally, it supports metastatic growth in breast cancer and serves as a biomarker for breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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