Thermo Fisher Scientific S100B Monoclonal Antibody (9A11B9)
S100B 단백질을 인식하는 Mouse 모노클로날 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, IHC, ELISA에 사용 가능하며, E. coli에서 발현된 정제된 S100B 단편을 면역원으로 제작되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9A11B9 |
| Immunogen | Purified recombinant fragment of S100B expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10989335 |
Product Specific Information
MA5-15359 targets S100B in indirect ELISA, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15359 immunogen is a purified recombinant fragment of S100B expressed in E. coli.
Target Information
S100B is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs.
S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of various cellular processes such as cell cycle progression and differentiation.
S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca²⁺ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly.
Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer’s disease, Down’s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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