Thermo Fisher Scientific E2F6 Polyclonal Antibody
E2F6 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 1 mg/mL 액상 형태입니다. 세포 주기 조절 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human E2F6 (amino acids 151–281) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA and 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The E2F6 gene encodes a member of the E2F transcription factor family, which plays a crucial role in cell cycle regulation and tumor suppressor protein activity. Unlike other E2F members, E2F6 lacks transactivation and tumor suppressor association domains but contains a modular suppression domain that inhibits E2F-dependent transcription. It forms part of a multimeric complex with histone methyltransferase and transcription factors Mga and Max. Multiple transcript variants exist, though their functional isoforms are not clearly established.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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