Thermo Fisher Scientific ZC3H13 Polyclonal Antibody
Rabbit polyclonal antibody against human ZC3H13 protein. Validated for IHC (Paraffin) at 1:500–1:1,000 dilution. Antigen affinity purified and supplied in PBS with 40% glycerol. Recommended storage at 4°C short term or -20°C long term. For research use...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZC3H13. Recombinant protein control fragment (Product # RP-97942) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649802 |
Product Specific Information
Immunogen sequence:
DSDAYNSGDD KNEKHRLLSQ VVRPQESRSL SPSHLTEDRQ GRWKEEDRKP ERKESSRRYE EQELKEKVSS VDKQREQTEI LESSRMRAQD IIGHHQSEDR ETSDRAHDEN KKKAK
- Highest antigen sequence identity:
- Mouse: 81%
- Rat: 79%
Target Information
The zinc finger CCCH domain-containing protein 13 (ZC3H13) is a 1668 amino acid protein that contains one C3H1-type zinc finger. ZC3H13 is phosphorylated upon DNA damage, most likely by ATM or ATR. Two isoforms of ZC3H13 exist as a result of alternative splicing events.
The gene encoding ZC3H13 maps to chromosome 13, which contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include BRCA2 and RB1.
Polysomy or trisomy of chromosome 13 (Patau syndrome) is deleterious to development and associated with severe neurological and respiratory defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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