Thermo Fisher Scientific NCF2 Recombinant Rabbit Monoclonal Antibody (ARC0828)
Thermo Fisher Scientific의 NCF2 Rabbit Recombinant Monoclonal Antibody (ARC0828)은 인간 NOXA2/p67phox 단백질의 200–300 아미노산 서열 기반으로 제작된 항체입니다. Western blot, IHC, ELISA에 적합하며 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0828 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 200–300 of human NOXA2/p67phox (P19878) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849294 |
Product Specific Information
Immunogen sequence:
GKATVVASVV DQDSFSGFAP LQPQAAEPPP RPKTPEIFRA LEGEAHRVLF GFVPETKEEL QVMPGNIVFV LKKGNDNWAT VMFNGQKGLV PCNYLEPVEL R
Target Information
NCF2, NCF1, and a membrane-bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Defects in NCF2 cause chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2).
Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill ingested microbes, leading to life-threatening bacterial and fungal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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