Thermo Fisher Scientific CYP2E1 Polyclonal Antibody
CYP2E1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간 CYP2E1 C-말단 펩타이드로부터 유래되었으며 비결합형 액상 형태로 제공됩니다. 약물 대사 및 간 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from C-terminal of human Cytochrome P450 2E1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635376 |
Product Specific Information
This antibody detects endogenous levels of total CYP2E1 protein.
Target Information
The CYP2E1 gene encodes a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. The protein localizes to the endoplasmic reticulum and is induced by ethanol, diabetes, and starvation. It metabolizes both endogenous substrates (ethanol, acetone, acetal) and exogenous substrates (benzene, carbon tetrachloride, ethylene glycol, nitrosamines). Due to its wide range of substrates, CYP2E1 is implicated in processes such as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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