Thermo Fisher Scientific FBXO8 Polyclonal Antibody
FBXO8 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 인간 및 마우스 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. -20°C에서 보관하며 연구용으로 사용됩니다.
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- PA5109714
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 110–250 of human FBXO8 (NP_036312.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.61 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855125 |
Product Specific Information
Immunogen sequence:
GLCKSTWGHC SIYNKNPPLG FSFRKLYMQL DEGSLTFNAN PDEGVNYFMS KGILDDSPKE IAKFIFCTRT LNWKKLRIYL DERRDVLDDL VTLHNFRNQF LPNALREFFR HIHAPEERGE YLETLITKFS HRFCACNPDL M
Target Information
The FBXO8 gene encodes a member of the F-box protein family, characterized by an approximately 40 amino acid F-box motif. These proteins are part of the ubiquitin protein ligase complex SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. F-box proteins are divided into three classes:
- Fbws: containing WD-40 domains
- Fbls: containing leucine-rich repeats
- Fbxs: containing other interaction modules or no recognizable motifs
The FBXO8 protein belongs to the Fbxs class. It has a C-terminal region similar to yeast Sec7p, a regulator of vesicular protein transport, and may interact with ADP-ribosylation factors (ARFs) to exhibit ARF-GEF activity.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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