Thermo Fisher Scientific ATF1 Monoclonal Antibody (OTI8G3), TrueMAB
ATF1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot과 IHC(Paraffin)에서 검증됨. 인간 시료에 반응하며, 고순도 친화 크로마토그래피로 정제. PBS/BSA/glycerol buffer에 보관되며 -20°C에서 안정적.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8G3 |
| Immunogen | Full length human recombinant protein of human ATF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an activating transcription factor belonging to the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates downstream gene expression involved in growth, survival, and other cellular processes. The protein is phosphorylated at serine 63 by multiple kinases, enhancing its transcriptional activity and cell transformation potential. Gene fusions with FUS (chromosome 16) or EWSR1 (chromosome 22) can produce chimeric proteins associated with angiomatoid fibrous histiocytoma and clear cell sarcoma. A pseudogene exists on chromosome 6.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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