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Thermo Fisher Scientific YTHDF2 Polyclonal Antibody
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Thermo Fisher Scientific YTHDF2 Polyclonal Antibody

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YTHDF2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간, 쥐 등 다양한 종에 반응. m6A 함유 RNA 결합 및 mRNA 안정성 조절 연구에 활용 가능. 액상 형태로 제공되며 -20°C 보관.

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pk
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마지막 업데이트 2025. 08. 03. 오후 02:18
Thermo Fisher Scientific PA570853 YTHDF2 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
642,300원VAT 포함 706,530원

Thermo Fisher Scientific · Thermo Fisher Scientific YTHDF2 Polyclonal Antibody

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Product Specifications

항목 내용
Species Reactivity Human
Published Species Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide directed towards the C-terminal region of human YTHDF2
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 2% sucrose
Contains 0.09% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Wet ice
RRID AB_2689883

Product Specific Information

This target displays homology in the following species:
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%


Target Information

YTHDF2 specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs and regulates mRNA stability.

  • M6A is a modification present at internal sites of mRNAs and some non-coding RNAs, influencing splicing, processing, and stability.
  • Acts as a regulator of mRNA stability by binding to m6A-containing mRNAs and localizing them to decay sites (P-bodies), leading to degradation.
  • Promotes cap-independent mRNA translation following heat shock stress by relocating to the nucleus and binding mRNAs with m6A at the 5'-UTR, protecting them from demethylation by FTO.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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