Thermo Fisher Scientific IFIT5 Polyclonal Antibody
Human IFIT5 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 0.1 mg/mL 농도. 바이러스 RNA 인식 연구 및 선천 면역 반응 분석에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IFIT5. Recombinant protein control fragment (Product #RP-97124). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642640 |
Product Specific Information
- Immunogen sequence:
FQEFHRKSEN TAIHHYLEAL KVKDRSPLRT KLTSALKKLS TKRLCHNALD VQSLSAL - Highest antigen sequence identity to orthologs:
Mouse – 44%, Rat – 51%
Target Information
Interferon-induced RNA-binding protein involved in the human innate immune response.
Has broad and adaptable RNA structure recognition important for antiviral defense.
Binds precursor and processed tRNAs as well as poly-U-tailed tRNA fragments (PubMed:25092312, PubMed:23317505, PubMed:23774268).
Specifically binds single-stranded RNA bearing a 5′-triphosphate group (PPP-RNA), acting as a sensor of viral RNAs.
Recognizes AT-rich dsDNA and regulates IKK-NFKB signaling by recruiting IKK to MAP3K7 (PubMed:26334375).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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