Thermo Fisher Scientific TPPP Polyclonal Antibody
TPPP 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 고순도 항원 친화 크로마토그래피 정제. PBS 및 50% 글리세롤 보존액, -20°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Tubulin Polymerization Promoting Protein (TPPP), amino acids 8–210 of the target protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903986 |
Target Information
Tubulin family members are globular proteins critical for microtubule assembly. Microtubules are essential structural components involved in mitosis, cytokinesis, and vesicle transport.
TPPP (Tubulin polymerization-promoting protein), also known as p24 or p25, is a 219 amino acid protein localized in the perinuclear region of the cytoplasm. It may form dimers and promotes tubulin polymerization into double-walled tubules or stabilized aggregates.
Overexpression of TPPP can inhibit mitotic spindle assembly and nuclear envelope breakdown. It is phosphorylated by TPK II and encoded by a gene on human chromosome 5.
TPPP plays a role in microtubule polymerization, bundling, and stabilization, maintaining microtubule network integrity and contributing to mitotic processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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