Thermo Fisher Scientific PSD93 Polyclonal Antibody
PSD93 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 사용 가능. 인산화 및 비인산화 형태 모두 검출 가능. 인간, 생쥐, 랫트 반응성. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:200–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region (phospho S28) of human PSD93 (DLG2) conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: PSD93. This antibody can recognize both the phosphorylated and unphosphorylated target.
Target Information
PSD-93 (also known as chapsyn-110) is a plasma membrane-associated protein found in synaptic junctions. It is expressed in Purkinje neuron cell bodies and dendrites. PSD-93 contains three PDZ domains, one SH3 domain, and an enzymatically inactive Guanylate Kinase (GuK) domain.
It participates in clustering of NMDA receptors and shaker-type potassium channels at synaptic membranes through PDZ-domain interactions, contributing to neuronal plasticity.
PSD-93 interacts with proteins sharing a T/SXV motif and can also associate with neuronal nitric oxide synthase (nNOS) via PDZ-PDZ interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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