Thermo Fisher Scientific PDE8B Polyclonal Antibody
Rabbit polyclonal antibody targeting human PDE8B (residues 835–885). Validated for Western blot and immunoprecipitation. Supplied as liquid, 1 mg/mL, stored at 4°C. For research use only.
- 카탈로그번호
- A303060Ax (2개 옵션)
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested amount: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 835 and 885 of human Phosphodiesterase 8B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of the 5′,3′-cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5′-monophosphates. Mammalian PDEs are grouped into several families based on substrate affinities, inhibitor sensitivities, regulatory mechanisms, and sequence homologies.
The PDE8 family includes high-affinity, cAMP-specific, IBMX-insensitive enzymes such as PDE8B. All PDEs share a conserved C-terminal catalytic region and a variable N-terminal domain that contributes to their distinct regulatory properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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