Thermo Fisher Scientific USP11 Polyclonal Antibody
USP11 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 polyclonal 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 0.5 mg/mL 농도의 액상 형태입니다. TBS buffer(pH 7.3)로 보관하며, -20°C에서 냉동 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (CSSPPSSEFMDVN) corresponding to the C-terminus amino acids of USP11 (aa 951–963). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983777 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the ubiquitin pathway. It localizes to the nucleus and associates with Ran BP-M (Ran binding protein M) and the tumor suppressor BRCA2. Through these interactions, USP11 inhibits or reverses ubiquitination of these proteins. It is implicated in several X-linked retinal diseases and may play a role in tumor suppression due to its deubiquitinating activity toward BRCA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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