
Thermo Fisher Scientific PGAM2 Monoclonal Antibody (OTI1E12), TrueMAB
PGAM2 단백질을 인식하는 마우스 모노클로날 항체로, Western blot과 Immunocytochemistry에 적합합니다. HEK293T 세포에서 생산된 인간 PGAM2 단백질을 면역원으로 사용하였으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E12 |
| Immunogen | Full length human recombinant protein of human PGAM2 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, it is recommended to add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction between 3-phosphoglycerate (3-PGA) and 2-phosphoglycerate (2-PGA) in the glycolytic pathway.
PGAM is a dimeric enzyme composed of different isozymes: muscle (MM), brain (BB), and hybrid (MB).
The PGAM2 gene encodes the muscle-specific subunit of PGAM.
Mutations in PGAM2 are associated with muscle phosphoglycerate mutase deficiency, also known as glycogen storage disease type X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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